Metastasis is an inefficient process. In vivo videomicroscopy and cell-fate analysis have led to the conclusion that early steps in metastasis are completed very efficiently. By contrast ...

In these cases, new treatments—such as repurposed drugs identified in the study—could disrupt the metastasis process before it becomes life-threatening," Tiwari explains. For example ...

Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a “genetic signature” of 177 genes shared across multiple ...

"Metastases from many solid tumors are very ... To learn more about this process, the Brekken Lab worked with James Lorens, Ph.D., Professor of Biomedicine at the University of Bergen in Norway ...

Development of circulating tumor cells (CTCs) technologies holds promise for a better understanding of the fundamental biology of the metastasis process. Understanding the molecular profile of ...

These proteins process signals within cells and regulate ... This intervention can be used to prevent the formation of metastases. The results of the research have been published in Nature ...

Attracted by a combination of tissue and inflammatory factors (IL-6, IL-8), metastatic cells may also colonize the primary tumor in a process called 'tumor self-seeding'. [37] Despite all the ...