Chemotherapy targets cancer cells by disrupting DNA replication and mitotic processes, despite side effects on healthy cells.

André). Metronomic chemotherapy is based on the chronic administration of chemotherapeutic agents at relatively low, minimally toxic doses, and with no prolonged drug-free breaks Metronomic ...

The molecular basis and mechanisms of action of combining classic cytotoxic ... Three clinical rationales support the use of chemotherapy delivered concurrently with radiation.

Previous attempts to identify resistance mechanisms to chemotherapy had focused on DNA that encoded genes. Looking directly at genes is simpler because non-coding DNA can have complex ...

Final data demonstrate CM24 in combination with nivolumab and Nal-IRI/5FU/LV chemotherapy clear and consistent improvement ...

Researchers at the University of Virginia have discovered a new mechanism driving drug resistance ... tumors are notorious for their resistance to chemotherapy, due in part to their dense, poorly ...

We suggest, however, that a different mechanism may underlie much of the therapeutic action of rituximab in autoimmune diseases: binding of tens of thousands of rituximab−IgG molecules to B ...

Researchers at the University of Virginia have discovered a new mechanism driving drug resistance ... tumors are notorious ...