总的来说，搔抓与免疫反应的关系揭示了皮肤免疫疾病治疗的新方向。通过深入理解神经免疫交互作用，未来的研究有望开发出更加精确的治疗方法，不仅改善患者的临床症状，还可能从根本上恢复皮肤免疫功能。这一全新的治疗思路为过敏性皮肤病的管理带来了前所未有的希望，未 ...

IT has been demonstrated that, besides heparin and histamine, mast cells contain serotonin (5-hydroxytryptamine, 5-HT) 1–3. However, serotonin-containing mast cells, having been found ...

接下来，这个研究团队发现，抓挠会导致痛觉神经元释放一种名为P物质的化合物。反过来，P物质会激活肥大细胞，而肥大细胞是炎症的关键协调者，通过招募中性粒细胞来驱动瘙痒和炎症。

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially ...

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are excessively proliferated during food allergies, the precise mechanisms that ...

Scientists have now shown why it may not be a good idea to scratch an itchy rash, even though it feels good. This research ...

A new case report was published in Oncoscience's Volume 12 on February 4, 2025, titled “Breaking point: Systemic mastocytosis manifesting as severe osteoporosis.” ...

Scratching an itchy rash worsens inflammation by triggering pain-sensing neurons and activating mast cells, creating a ...

Researchers identified two anoikis-related genes linked with CTEPH, and that may serve as diagnostic biomarkers or treatment ...

Discover studies that have shown that psoriasis patients exhibit elevated intestinal permeability, correlating with ...