The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

Loeys-Dietz syndrome was identified in 2005 by then Johns Hopkins researcher Bart Loeys, M.D., Ph.D., and Hal Dietz, who directs Johns Hopkins' research on Marfan syndrome, a genetic disorder ...

Greater experience (1) has shown that articular laxity (Gscherend) is the cardinal symptoms of this important Marfan-related disorder and the spectrum of symptoms that vastly exceeds it ...