In parallel with the hunt to identify MYC target genes and their mechanisms ... and understand the main biological activity and pathway controlled by this potent oncogene. The successful MYC ...

But eventually, the immune-attracting pathways are turned off ... The study results strengthen the evidence that MYC may be a critical target for prostate cancer treatment or prevention ...

Our current research specifically focuses on therapeutic strategies aiming to exploit MYC oncogene-induced vulnerabilities and therapeutically intervenable ... and stem cell-based organoids as well as ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.