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腾讯网
26 天
Immunity | 抑制性共受体Lag3通过限制Myc依赖的代谢程序调节Treg细胞功能
在本研究中,作者特异性突变Treg细胞的Lag3受体,揭示了Lag3通过PI3K-Akt通路抑制Myc的表达,从而支持Treg细胞免疫抑制功能的分子机制。 为了探究Lag3 ...
腾讯网
5 天
Neuro Oncology | 3型髓母细胞瘤中发现可靶向的代谢节点
撰文 | 周馨 责编 | 周叶斌髓母细胞瘤是儿童中最常见的恶性脑部肿瘤之一,其中MBGRP3亚型特征为c-MYC(MYC)高表达,且治疗进展有限。近日,来自英国的研究组在 Neuro Oncology 发表了题为 MYC-dependent ...
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