Researchers have been trying for decades to stop the cells that damage the lung in people with pulmonary fibrosis. Now a team ...

Though not expected to replace animal models completely, human organoids could soon lead to significant reductions in research animal numbers, the team led by cell biologist and nanotoxicologist Dr ...

The researchers cultured the tissue-specific progenitor cells, fed them a chemical cocktail to support growth, and watched as they proliferated, differentiated, and self-organized into 3D epithelial ...

The organoids, based on pluripotent stem cells, reproduce in 3D a specific tissue, in this case the lung mucosa, which can be ...

This allows researchers to model organ-specific diseases, such as inflammatory bowel disease using gastrointestinal organoids, cystic fibrosis using lung organoids, and bladder cancer using urothelial ...

To address these fundamental questions, we employ a multidisciplinary approach integrating genetic mouse models with lineage-tracing techniques, primary mouse and human lung organoids with genetic ...

SINGAPORE: The Academic Respiratory Initiative for Pulmonary Health (TARIPH) Centre, led by Nanyang Technological ...

In one application of their work in collaboration with researchers in Belgium, the team grew lung organoids from the cells of ...

Scientists have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as ...

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic ...