Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...
Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...
Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...
In February 2024, the FDA put two Phase II studies of zelnecirnon under a clinical hold after a case of liver failure was deemed potentially related to the drug.
With some question marks lingering over key players, here are the latest Arsenal injury updates. No single player has managed to effectively replace Odegaard, though that hasn't stopped Arsenal from ...
In our 2022 study, my team and I found that activating a particular protein with a new medication can help accelerate regeneration and repair after severe liver injury or partial surgical removal in ...