this new work suggests the important role of linking neuronal mitochondrial failure to lipid-droplet accumulation in glial cells towards pathogenesis in aging and age-onset diseases,” Chopra said.

"Driven by a keen interest in lipid droplet functions in aging and disease, we initiated this fruitful collaboration to harness cutting-edge SRS technology for studying lipid metabolism in ...

Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in ...

"Considering the Mfn-2 functions in mitochondrial morphology and in the liver ... More information: Juan Carlos Bórquez et al, Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria ...

Droplet creation is a crucial but challenging subject in microfluidics. Depending on the application, the objective is to produce droplets of a particular size. Two immiscible phases are used in ...

Seipin forms a flexible cage at lipid droplet formation sites. Nat Struct Mol Biol. 2022 Feb 24. doi: 10.1038/s41594-021-00718-y. Online ahead of print. Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

Our goal is to elucidate the molecular mechanisms underlying these processes and their functional links to mitochondrial diseases. Additionally, our lab investigates how proteins shape diverse ...

Cancer cells may be using lipids to hide from the immune system Date: September 17, 2024 Source: Rockefeller University Summary: New study demonstrates that one type of lipid is so critical for ...

MitoRx Therapeutics (MitoRx), a platform biotechnology company developing novel mitochondrial-targeted sulfide-donor therapeutics (mtH2SD) in obesity-related disorders and myopathies announces a ...