Transform the verified clones into the cell lines of interest to test their ability to knock down gene expression. The vector(s) may be transiently transfected into any commonly used cell line ...

1 Scientists have harnessed RNAi in the laboratory to selectively silence target gene expression, a technique known as gene knockdown ... 9 Functional genomics researchers now commonly use RNAi to ...

Both gene knockout and knock-in models are powerful ... latter of which is associated with superior efficacy in knocking down ...

The vivid wing patterns of butterflies, once attributed to a gene, are now traced to an overlooked microRNA.

AMT-162 is an investigational AAVrh10-based gene therapy that expresses a miRNA designed to knock down the expression of the mutated SOD1 protein. Patients with SOD1-ALS express a misfolded SOD1 ...