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9 天
当糖遇上肾——探析SGLT2i在糖肾管理中的应用价值
SGLT2i是近年来备受瞩目的一类新型降糖药,其发挥肾脏保护作用的核心机制是通过抑制肾小管SGLT2,Na+的重吸收减少,导致远曲小管中Na+浓度升高,致密斑感受到Na+浓度升高后调节肾素的释放,收缩肾小球入球小动脉,降低囊内压,重建管球反馈10。此 ...
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