Are inhibitors of the JAK/STAT Signaling Pathway a potential treatment for Parkinson Disease? How does -syn lead to activation of the JAK/STAT pathway, and how does this contribute to ...

A recent study published by the lab in Nature Communications [2024; PMID: 38355560] sheds light on this aspect by elucidating the role of the IL6/JAK/STAT3 signaling pathway in driving bladder cancer ...

These mice also showed stronger signs of an inflammatory signaling pathway called the IL-6/JAK/STAT3 pathway—the same one the team had implicated in liver metastasis in their 2019 study.

Using innovative spatial proteomics—one of the most advanced molecular biology tools—the team identified the inflammatory JAK ...

which is an important kinase on the JAK-STAT signaling pathway and plays an important role in the pathogenesis of inflammatory diseases. Currently, no TYK2 inhibitors have obtained marketing ...