来自MSN3 天
Mutation Clearance After Transplant Linked to Better Outcomes in Myelofibrosis
Disease-free and overall survival rates at 6 years were 61% and 74%, respectively, among patients with mutation clearance at ...
Nature16 年
New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G
The other mutations are devoid of significant transforming activity but may synergize with JAK2 V617F or other not yet characterized molecular events. The study was approved by the Local Research ...
Medpage Today on MSN8 个月
Genetics and Genetic Testing to Inform Myelofibrosis Clinical Management
Another 45 years passed before the discovery of a first genetic driver of non-Ph MPNs, a mutation in the Janus kinase 2 (JAK2 ...
Cure Today25 天
Polycythemia Vera: Overview
A panelist discusses how polycythemia vera (PV) is a rare myeloproliferative neoplasm (MPN) characterized by excessive red blood cell production, primarily affecting older adults with JAK2 mutations, ...