[15] Jak3 and Jak1 are activated following ligand binding of the transmembrane receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21, all of which share a common γ-chain receptor. [17] Jak3 and ...

A once-daily dose of ivarmacitinib reduced disease activity and improved function among patients with rheumatoid arthritis ...