To explore the evolution and function of introns in eukaryotes, we have developed an intron sequence information system (ISIS; http://isis.bit.uq.edu.au/) which ...

1b). Within this complex, intron excision occurs in two steps, each a single transesterification reaction. In the first step, the 2'-OH of an adenosine in the intron (the branch site A ...

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...