Could interleukin-1 antagonists be the answer to managing acute gout? Guidelines for the management of this disorder, issued by the European League Against Rheumatism (EULAR) and the British ...

Interleukin-1 receptor-associated kinase 4 is critical in the modulation of inflammatory responses through Toll-like receptor and IL-1R signaling.

GNSC-001 is an investigational, adeno-associated virus gene therapy expressing an optimized form of interleukin-1 receptor antagonist (IL-1Ra), a protein that blocks interleukin-1 (IL-1) signaling. IL ...