This important study identifies the "H-state" as a potential conformational marker distinguishing amyloidogenic from non-amyloidogenic light chains, addressing a critical problem in protein misfolding ...

Neurofilament light chain (NFL) is a structural component of the neuronal cytoskeleton that is released into the blood during neurodegeneration. This webcast will cover the utility of NFL as a ...

Background: Monoclonal free light chains (FLCs) frequently cause rapidly ... that in patients with renal failure the FLC ratio can be increased above normal with no other evidence of monoclonal ...