a compound called BTS 8402 is given a clinical trial but it is found to be no better than aspirin 1961: A patent is filed for the compound 2-(4-isobutylphenyl) propionic acid - later called ibuprofen ...
They filed a patent for the compound 2-(4-isobutylphenyl) propionic acid - later called ibuprofen - in 1961. It was not until 1969, after years of clinical trials, that it was approved for use and ...
BMC Clin Pharmacol. 2010;10(10):1-12. Taken together these differing modes of action and related therapeutic effects suggest that ibuprofen and paracetamol may complement each other and improved ...