Restricted VLPO lesions produce partial sleep loss 5, but large rostral lesions 12 or transections just caudal to the rostral hypothalamus 13 can produce total sleep loss.

And so, a hypothalamic lesion can lead to appetite-related changes. Doctors say hyperphagia is common with all types of diabetes, including type 1, type 2, and gestational diabetes. It is a common ...

In animals, lateral hypothalamic lesions produce anorexia while VMN lesions produce hyperphagia. [29–33] In that context, more recent studies have demonstrated that appetite reflects the ...