Cranial radiotherapy in children and adults with brain tumors frequently causes abnormal hypothalamic-pituitary function. The most frequent changes are hypothyroidism and gonadal dysfunction ...

“While ‘adrenal fatigue’ isn’t an actual medical diagnosis, and it’s not an entirely accurate description of what’s happening, hypothalamic-pituitary-adrenal axis dysfunction and its ...

Tumor-induced chronic systemic inflammation causes endocrine dysfunction, reducing appetite (anorexia) by altering hypothalamic hunger and satiety centers, increasing protein catabolism in muscles, ...