circuit-by-circuit, with other hypothalamus-based systems that converse with the hypocretin neurons and other systems to establish the set points for which they shoulder primary responsibility.

A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact ...

More information: Dominik Groos et al, A distinct hypothalamus–habenula circuit governs risk preference, Nature Neuroscience (2025). DOI: 10.1038/s41593-024-01856-4 ...

This important study shows that the activity of hypothalamic hypocretin/orexin neurons (HONs) correlates with body movement over multiple behaviors. Sophisticated techniques and analyses showcase this ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

and medicine (how can we target specific brain signals to treat common diseases?). A key focus is on pan-CNS-projecting "brain orchestrator" circuits radiating from the hypothalamus, and postulated to ...

Emotional stress signals are processed in the 'emotion' circuits and integrated in the DP/DTT. The integrated signals are transmitted to the hypothalamus which then drives a variety of physical ...