Hypertrophic cardiomyopathy (HCM) was first described in the late 1950s as a disease typified by substantial thickening of the myocardium, particularly the left ventricular wall, with no overt cause.
Pulsus bisferiens was also commonly present in free aortic regurgitation and in hypertrophic subaortic stenosis. It has also been found in several high-cardiac-output states such as ...
Mavacamten is approved for treating obstructive hypertrophic cardiomyopathy, with real-world data supporting its safety and efficacy. The REMS program is crucial for monitoring mavacamten's safety ...
A study has found that aficamten is associated with improvements across a range of clinical outcomes in patients with obstructive hypertrophic cardiomyopathy.