How do neurons manage to become self-organized, accurately balancing protein removal from synapses and trafficking into synapses on demand, when the spine volume is dynamically modulated?

This important study introduces rationally designed, genetically encoded tools for the selective and reversible ablation of excitatory and inhibitory synapses. The evidence is convincing, supported by ...

However, it was previously unclear how the neurons implement these changes in strength across several synapses that are close ...

To form a synaptic connection in the CNS, neurons need to accumulate all the machinery of the synapse at the point ... granule neuron dendrites. Previous work (reviewed in ref.

Recalling those new words and definitions more easily with practice is evidence that those neural connections, called synapses ... Sejnowski says future work by projects like the National ...