Iron overload, characterized by elevated serum ferritin levels, has long been associated with various systemic complications ... Importantly, among high-risk patients presenting with serum ferritin ...

C282Y homozygous patients with normal or mildly elevated ferritin can undergo frequent monitoring of SF and TS and treatment should not be initiated if their levels remain stable. C282Y/H63D ...

Treatment depends on whether ferritin and iron levels are too high or low. Phlebotomy (therapeutic blood removal): Regular ...

A phase 3 trial highlights betibeglogene autotemcel as a potentially curative gene therapy for severe transfusion-dependent β ...