The paradigm of stellate cell activation provides an important ... The most effective way to eliminate hepatic fibrosis is to clear the primary cause of liver disease. The latter includes ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that drive hepatic fibrosis. These immunomodulatory, antifibrotic, and liver ...

17 in Molecular Cell, provides new insights into a pair of proteins, called p62 and NBR1, and their opposing functions in regulating the interferon response in hepatic stellate cells, a critical ...

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be ...

The two other genes, MAT2A and MAT2B, are active within a second kind of liver cell called stellate cells, which also play a ...

Learn about HMGB1's crucial role in liver diseases, its pathways and therapeutic potential that can treat liver diseases.