This study successfully reproduced the developmental process of hematopoietic stem cells (HSCs) in an in vitro culture system using commercially available endothelial cell lines as feeder cells ...

The result was the successful induction of HSCs from embryo-derived hemogenic endothelial cells, demonstrating the method's ...

The culture system established in their study reproduces the microenvironment where HSC development occurs and has successfully differentiated mouse embryo-derived hemogenic (blood-producing) ...