Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric ...

When you think of arthritis, achy, warm, swollen joints probably come to mind. These are indeed some of the most common ...

Patients with tophi also had significantly greater impairment of work productivity and activity. Tophaceous gout was associated with greater absenteeism and overall work impairment than both the ...

Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

with gout. Mean patient age was 56.3 years, and mean disease duration was 9.3 years. In all, 52.4% of patients had joint pain, 22.8% had swelling, 32.5% had reduced mobility and 36.9% had tophi.

Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and inflammation associated with acute gout. As demonstrated in a novel mouse model ...

Untreated gout places a substantial burden on the global health system, as chronic gout causes tophi formation, chronic joint pain, and erosion and damage to joints, resulting in an increase in ...

Doctor Edward Dwyer knows gout when he sees it. The throbbing agony drives many patients to seek medical help. Doctors generally prescribe one of three different treatments fo this type of searing ...

Gout is a form of inflammatory arthritis that causes severe pain and swelling in one or more of your joints. These attacks happen suddenly when there's a buildup of uric acid, a chemical found ...