The glomerular basement membrane (GBM) is a specialized form of basement membrane that has a major role in the maintenance of the glomerular filtration barrier. Like all basement membranes ...
Anti-glomerular basement membrane (anti-GBM) antibodies were present in the patient's serum, and eosinophils were noted in his urine. Renal biopsy revealed active crescents, with linear staining ...
However, in mice with anti-glomerular basement membrane (GBM) nephritis, these tight junctions were disrupted when PECs detached from the underlying Bowman's basement membrane. To investigate the ...
Immunofluorescence microscopy disclosed linear staining of the glomerular capillary basement membrane for IgG ... Diagnoses of anti-GBM antibody disease with active crescents, acute tubulo ...