The investigational monoclonal antibody nipocalimab is associated with significant improvement in patients with generalized ...

The neonatal Fc receptor (FcRn) is important for numerous cellular processes that involve antibody recycling and trafficking. A major function of FcRn is IgG recycling and half-life prolongation, and ...

The MHC class I-like molecule FcRn is an intracellular trafficking receptor with diverse and critical immune system functions. 1-3 It is unique in being able to extend the half-life (a measure of ...

Immunovant, Inc. shifts focus to anti-FcRn antibody IMVT-1402, but high R&D costs and uncertainty warrant caution for ...

Investigational nipocalimab lessened disease severity in generalized myasthenia gravis (gMG), the phase III Vivacity-MG3 ...

In fact, IgG is the only Ig that is known to cross the placenta, which is does via the FcRn receptor. “Alloimmunization affecting pregnancy represents perhaps the most elegant and simple potential ...

The IgG Receptor FcRn Large Subunit p51 pipeline drugs market research report outlays comprehensive information on the IgG Receptor FcRn Large Subunit p51 targeted therapeutics, complete with analysis ...

Objectives Potent monoclonal antibodies (mAbs) which specifically inhibit IgG-FcRn interaction, but not albumin-FcRn interaction were developed to determine the potential of FcRn blockade to clear IgG ...

Halozyme Therapeutics, Inc. (NASDAQ: HALO) today announced that argenx has nominated four new targets under its global ...

Halozyme Therapeutics, Inc., a biopharmaceutical company, announced that argenx has nominated four new targets under its global collaboration and license agreement that provides argenx exclusive ...