These drugs function by blocking synthesis of the enzymes used to release these fatty acids from the cell membrane, preventing the synthesis of prostaglandins. Steroid drugs are commonly used to ...

First, PlsX catalyzes the synthesis of the intermediate fatty-acyl-phosphate (acyl-P) from acyl-ACP. Next, PlsY transfers the fatty acid from the activated acyl intermediate to the 1-position of G3P.

Using fermentation, University of Alberta researchers have come up with a way to produce higher amounts of a healthy fatty acid found ... involved in punicic acid synthesis and accumulation ...

The work of his group on giant multifunctional enzymes involved in fatty acid synthesis offer first mechanistic insights into substrate shuttling and delivery in such megasynthases, with direct ...