IgG activates complement, and binds Fc-receptors (FcRs) on macrophages and neutrophils, upon which pathogens coated with IgG are phagocytosed by these cells. 14 Intriguingly, obesity is associated ...

Here we describe a mouse Fc receptor, designated Fcα/μR ... Although the polymeric immunoglobulin receptor, which also binds IgM and IgA, is expressed on epithelial cells, it is unclear whether ...

IgG is the most abundant type of immunoglobulin in the extracellular fluid. Its ability to bind Fc receptors on phagocytic or other lytic effector cells enables the initiation of antibody ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...