Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction ...

Epigenetics can contribute to understanding interindividual differences in the expression of drug transporters and drug-metabolizing enzymes, thus providing an additional basis for the explanation ...

Epigenetics is the study of various heritable alterations that control gene expression ... looped spatially and where…distant regions of DNA are touching,” Cosgrove added. “There are these clinically ...

New research about how smoking damages DNA could open new possibilities for targeted cancer prevention. Israeli and US ...

The new drug strategy is the culmination of an intensive investigation into ways to target and block proteins that facilitate cancer-specific epigenetic changes in cells. Epigenetics ("on top of ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

The review also points out the potential of epigenetic drugs in cancer treatment, with several drugs already approved by the US Food and Drug Administration (FDA) for clinical use. Cardiovascular ...

New findings from researchers at the University of California San Diego School of Medicine have clarified the interplay between two major molecular contributors to aging: genetic mutations and ...