Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

Promoters, which start gene transcription, showed a dependence on sequence orientation but were less specific to cell types. Enhancers, which boost gene transcription, were active regardless of ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for ...

“We didn’t think it would work.” The results serve as an extreme example of what scientists are now recognizing as trends among enhancers—that activity can be conserved over long evolutionary ...

Some of these “enhancers” regulatory sequences function similarly to the dimmer switches that control the lighting in the living room. In fact, when and where a specific gene is needed ...

They looked for gene control elements called "enhancers" — short DNA sequences that can activate associated genes when bound by specific proteins. Because genetic enhancers are highly tissue ...