This increase in ER capacity is physically achieved by an increase in size of the ER at early stages of autophagy, see figure. If the protein folding demand continues to increase, this will ultimately ...

Cells adjust the expansion and networking of their internal canal system as needed. A process known as ER-phagy ("ER-eating") plays a central role here. During this process, a part of the membrane ...

The ER-phagy receptor FAM134B is initially distributed via the membrane surface (left). Its IDRs move back and forth in a largely disordered manner, like tentacles. The formation of local clusters ...

Cells adjust the expansion and networking of their internal canal system as needed. A process known as ER-phagy ("ER-eating") plays a central role here. During this process, a part of the membrane ...