Adhesion G protein-coupled receptors (aGPCRs ... there are no drugs approved to target aGPCRs because they are large, complex, and difficult to study. New research from the University of Chicago ...
Their findings highlight the ... targeting androgen receptor (AR) signaling, such as taxanes and newer agents, show limited success. Cisplatin, a widely used anticancer drug, has been used in ...
Computer modeling of the three-dimensional receptor-inhibitor complex by Professor Jens Meiler's group at the Institute for Drug Discovery confirmed this insight. "These findings make a ...