What happens in the brain when we drink alcohol? Scientists have taken a significant step toward answering this question by ...
Also, the duration of the drug effect is related to the association and dissociation rates of the drug–receptor complex.
Adhesion G protein-coupled receptors (aGPCRs ... there are no drugs approved to target aGPCRs because they are large, complex, and difficult to study. New research from the University of Chicago ...
Researchers at the University of Chicago have successfully captured detailed images of adhesion G protein-coupled receptors, ...
Their findings highlight the ... targeting androgen receptor (AR) signaling, such as taxanes and newer agents, show limited success. Cisplatin, a widely used anticancer drug, has been used in ...
Computer modeling of the three-dimensional receptor-inhibitor complex by Professor Jens Meiler's group at the Institute for Drug Discovery confirmed this insight. "These findings make a ...