2003 ). For example, when expressed in the Drosophila brain, Tau protein—which forms neurofibrillary tangle pathology in AD—causes adult onset, progressive neurodegeneration, truncated lifespan and ...

“It took us 18 months or two years, almost, to work out the genetic tools we needed so that we can manipulate the NPF in the gut without affecting the NPF in the brain.” Researchers also had to ...

The Colombani Andersen lab at the section of Cell & Neurobiology, Department of Biology, University of Copenhagen uses the ...