Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

One distinct feature of transcription factors is that they have DNA-binding domains that give them the ability to bind to specific sequences of DNA called enhancer or promoter sequences.

Because Mediator interacts with both DNA-binding TFs and the general transcription machinery (including pol II), Mediator acts as a molecular bridge to link these factors and facilitate TF-dependent ...

In genetics, it has generally been accepted that each gene has one transcription initiation site, located downstream of a core promoter region and typically around a TATA box — a DNA sequence ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

Generally, they were not, as the proteins targeted promoter regions of DNA and the three prime untranslated ... polyadenylation and altering mRNA after transcription via enzymes through a process ...