Reseachers from WEHI (Melbourne, Australia) have found a new way to predict a subset of patients who are likely to become ...

The splicing reaction would happen inside the speckle ... kinetic coupling of two very diverse but critically integrated processes is achieved through physical spatial organization, remodeling of DNA ...

Gene mutations have consequences both good and bad—from resistance to conditions like diabetes to susceptibility to certain ...

Researchers unveil the inner mechanisms of the most intricate and complex molecular machine in human biology. Scientists at the Centre (CRG) in Barcelona have developed the first comprehensive ...

for example those targeting mutations in DNA, often cause cancer cells to become resistant. One of the ways cancers adapt is by rewiring their splicing machinery. Targeting splicing can push ...

Non-coding parts of a gene, called introns, are typically removed as a gene's DNA is transcribed into an RNA version in a process called splicing. Cancer cells can interfere with splicing to create ...

GENETIC researchers in Barcelona have reached a historic milestone, creating the very first map of the spliceosome. A key ...

Compared to DNA sequencing alone, concurrent DNA and RNA sequencing revealed more clinically actionable variants in NSCLC.

Alternative splicing is crucial for eukaryotic gene expression and influences protein function and regulation, with mis-splicing linked to numerous diseases. In this webinar, Dr. Megan L Noonan will ...

A new approach for identifying new cellular RNA targets of snoRNAs uncovered thousands of previously unknown targets ...

Harvard researchers pioneered a method called HACE for targeted gene mutations, advancing genetic research potential.