Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval.

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

A colorectal surgeon named Dr Cedrek McFadden has shared the top five reasons why people may be at risk of getting colorectal ...

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase ...

The younger the age when cancer develops, the more likely the disease is to be related to a particular genetic defect. Patients should also be questioned about family members who have colon polyps ...

Explore how genetic testing and precision oncology are revolutionizing cancer treatment by offering personalized care and ...

A groundbreaking study has uncovered how specific genetic mutations influence cancer treatment outcomes -- insights that could help doctors tailor treatments more effectively. The largest study of its ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

Genetic mutations-changes in DNA-can influence how cancer develops and how a patient responds to treatment. Some mutations occur randomly, while others are inherited.

The 32-year-old teacher had two pregnancies since she found out she had inherited a gene that contributed to her colorectal cancer, which was diagnosed in August 2020. Her first pregnancy occurred ...