These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...

When these switches were applied to colon cancer cells, the cancer cells reverted to a normal-like state, a result confirmed through molecular and cellular experiments as well as animal studies.

The cell type and the genetic mutations that give rise to the tumors and the effect of the tumor microenvironment on their growth can vary widely. This diversity can lead to incorrect characterization ...