Additionally, a few Melaps-induced phase shifts in Period1::luc transgenic (Tg) mice were used to monitor circadian rhythms ...

particularly those engaged in rotating night shifts, experiencing sleep disorders by comprehending how the central body clock or the circadian rhythm functions normally, said Michael Hastings ...

Advt "Notably, daily circadian phase shifts were the most significant predictors: delays linked to depressive episodes and advances to manic episodes," the authors of the study added.

Using training data from the 60-day range, the model accurately predicted next-day depressive, manic, and hypomanic episodes, with AUC (Area Under the Curve) values of 0.80 ... The study also finds ...