Ceramides or their metabolites could contribute to adverse effects of long-chain fatty acids on insulin resistance and inflammation. In the present study, we reasoned that fat accumulation in the ...

A recent study published in Life Metabolism reports that high temperature can ameliorate insulin resistance by promoting ceramide catabolism in skeletal muscle tissue (SMT) of obese mice.

We recently reported that insulin resistance is not generally normalized ... content and reductions in IMTG and intramyocellular ceramide but not DAG. RYGB surgery–induced weight loss enhanced ...

"Rising ceramides in the cell are responsible for inflammation, insulin resistance, and cell death," said study leader Philipp Scherer, Ph.D., Professor of Internal Medicine and Cell Biology and ...