A dopa decarboxylase inhibitor (DDCI), such as carbidopa or benserazide, is administered with levodopa to attenuate its peripheral conversion to dopamine, reduce nausea and increase central ...

Combining levodopa with a DDC inhibitor (DDCI), such as carbidopa or benserazide, greatly reduces the incidence of nausea and vomiting, increases the levodopa half-life from approximately 60 to 90 ...