When Cre recombinase (red circle) is introduced, either as a transgene by crossing into a mouse line carrying the targeted gene locus or on a viral vector, the DNA between the loxP sites (red ...

Figure 2: Induction of Cre-mediated recombination from the Cre-ERT2 transgene 29 leads to death of c-Myc-driven primary B cell lymphomas. References Glaser, S., Anastassiadis, K. & Stewart, A.F ...

Ad5-CMV-Cre-eGFP expresses the Cre recombinase protein along with ... Ad5-CMV-Empty Ad5-Empty virus contains a CMV promoter and poly(A) but no transgene. This virus is often used as a control virus in ...