Depletion of cellular immunity as a consequence of conditioning before allogeneic hematopoietic SCT (HSCT) frequently results in CMV reactivation, which may in turn lead to life-threatening ...
Transmission also can occur sexually and through blood transfusion and organ transplantation from an infected donor. [2] Approximately 40-90% of adults have antibodies to CMV (i.e., they have been ...
CMV is one of the most common and serious post-transplant infections with an estimated incidence rate of between 16% and 56% in solid organ transplants, and 30% to 70% in HSCT procedures.
More than 55% of transplant recipients with refractory CMV infections achieved confirmed viral clearance with Takeda's drug, compared to around 24% of those on conventional antivirals.
The impact of prophylactic oral ganciclovir therapy on the incidence of cytomegalovirus (CMV) disease, patient and graft survival, and costs in patients receiving kidney and liver transplants is ...
What is a stem cell and bone marrow transplant? Having a transplant means destroying as many cancer cells as possible and replacing these with healthy stem cells. Transplants use very high doses of ...
Dr. Adam Geballe studies the ongoing tug of war between virus and host. In particular, he focuses on cytomegalovirus, or CMV, a common, usually benign, infection. It can cause problems in people with ...