In order to address the underlying biology of the disease, we discovered multiple CFTR modulator therapies with distinct and novel mechanisms of action. We have brought forward four medicines that ...

Join Peter Grootenhuis of Vertex Pharmaceuticals as he delivers a brief overview of the drug discovery approaches and challenges to identify small molecules CFTR modulators. These compounds improve ...

Knowing this, in the early 2000s, researchers began to look for treatment options that addressed the root cause of CF, ...

Other rare mutations that are not eligible for CFTR modulators will be explored as the editing technology matures. “Gene editing is a promising, complex technology, which will take many years to ...

The drug for CF (CFTR modulators), while under monopoly, continues to be unavailable in the country due to a lack of registration by Vertex (the patentee) with the Indian FDA and is priced at one ...

Other rare mutations that are not eligible for CFTR modulators will be explored as the editing technology matures. "Gene editing is a promising, complex technology, which will take many years to ...

The firm's chief scientific officer called the achievement "a major milestone for Spirovant and for the cystic fibrosis ...