CSF is important because whatever is in the fluid can cross over to affect brain function and activity. There are a few possible ways that the blood-brain barrier can be weakened, including ...

The powerful blood-brain barrier, the thinking goes, keeps the organ mostly free from outside invaders. But are we sure that a healthy human brain doesn’t have a microbiome of its own?

The therapy was well tolerated in the trial and showed the ability to cross the blood-brain barrier. The levels of the therapy in the CSF were comparable to or exceeded those in plasma ...

Human metapneumovirus, usually known for respiratory infections, can—though rarely—trigger life-threatening brain inflammation.

Penn Engineers have modified lipid nanoparticles (LNPs)—the revolutionary technology behind the COVID-19 mRNA vaccines—to not only cross the blood-brain barrier (BBB) but also to target ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Danielle Wilhour, University of Colorado Anschutz Medical Campus (THE CONVERSATION ...