This is maintained by the blood–brain barrier, whereby specialized brain endothelial cells lining the inner walls of blood vessels regulate the exchange of molecules between the circulatory and ...
Stimulated release of endothelium-derived NO results in vessel dilation and elevated blood flow ... is influenced by NO produced by endothelial cells and by platelet-derived NO.
Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy.