The two apoptosis pathways of interest are the extrinsic ... (DRs), and the intrinsic pathway is tightly controlled by the BCL-2 family of proteins and involves the disruption of mitochondrial ...

Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways ... required for apoptosis activation in C. elegans. However, minor proapoptotic roles for drp-1 and fis-2, a ...

From early development to old age, cell death is a part of life. Without enough of a critical type of cell death known as ...

From early development to old age, cell death is a part of life. Without enough of a critical type of cell death known as ...

Ascentage Pharma's BCL-2 inhibitor, lisaftoclax, is under China’s Priority Review for chronic lymphocytic leukemia and small ...

Ascentage Pharma (6855.HK) is a global, integrated biopharmaceutical company engaged in discovering, developing and commercializing therapies to address global unmet medical needs primarily in ...

Annexin V (AV) and Bcl-2 were evaluated for apoptosis ... improved EPC survival and inhibited apoptosis while promoting ...