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腾讯网
1 个月
The Innovation | 实体瘤BRAF基因突变临床诊疗国际专家共识
IHC利用特定抗体检测BRAF V600E突变蛋白,操作简便且成本低,但容易得出假阳性结果。NGS是一种高通量技术,能够检测广泛的BRAF突变,包括低丰度 ...
腾讯网
18 天
肠癌诊疗期间,这些基因必须检测!
BRAF V600E突变患者相比其他患者预后更差 ... 没有任何位点显示MSI,即MSS。 MMR蛋白的IHC检测,需同时检测4个常见MMR蛋白(MLH1、MSH2、MSH6和PMS2)的表达。其中≥1 种表达缺失,判定为错配修复基因缺陷(dMMR ...
Medscape
7 天
The Diagnostic Role and Clinical Relevance of Determination of BRAF Status in Brain Tumors
BRAF V600E mutations are common in different tumor types (more frequently in melanomas, colon and thyroid carcinomas). BRAF Alterations in Brain Tumors: Different Diagnostic Relevance of BRAF ...
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